Lab Introduction

Our expertise lies in the field of molecular medicine, with a long-standing dedication to head and neck cancer research. Through years of foundational research and clinical observations of head and neck cancer patients, I integrate clinical and scientific aspects closely. Since 2007, I have been focusing on a series of studies centered around the deterioration of head and neck cancer, yielding fruitful results. Over the years, I have published over 150 papers, with 10 articles in top-tier journals such as Cell and the Nature series. These journals include Nature Cell Biology (2008, 2010, 2012, 2014, 2019), Cancer Cell (2014), Cell Reports (2016), Nature Communications (2018, 2018), and Cell Reports Medicine (2023). Many of these papers have garnered over 200 citations, with the research published in Nature Cell Biology in 2008 being cited over 1300 times, the 2010 publication in Nature Cell Biology being cited over 600 times, and the 2014 publication in Nature Cell Biology being cited over 250 times. This demonstrates the significance of these studies in cancer biology, providing critical perspectives for both fundamental and medical sciences. By combining innovative molecular mechanism exploration and clinical validation of immunotherapy, these studies have made significant contributions to the understanding and treatment of head and neck cancer.

Research Topic (1): Mechanisms of Epithelial-Mesenchymal Transition Inducing Cancer Stem Cells

Research Topic (2): Mechanisms of Epithelial-Mesenchymal Transition Regulating the Tumor Immune Microenvironment

Research Topic (3): Mechanisms of Collective Cell Migration and Circulating Tumor Cell Regulation by Epithelial-Mesenchymal Transition Factors

Research Topic (4): Mechanisms of Ferroptosis-Induced Tumor Inflammatory Response and Enhanced Immunotherapeutic Efficacy

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